Benzodiazepines: Best Practices in Primary Care
The Best Practices in Primary Care Bulletin offers best practices for benzodiazepine prescribing in primary care, including indications for prescribing, when to offer and optimize non-pharmacologic first-line treatments, potential risks associated with long-term prescribing, and when de-prescribing may be appropriate. The supplementary and summary materials are intended to support the use of this bulletin by offering concise, practical summaries and tools for use at point-of-care.
Note:
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- These best practices are relevant for individuals prescribed benzodiazepine receptor agonists (BZRAs) who may or may not meet criteria for benzodiazepine use disorder
- Some of these best practices may be applicable to those who have been intentionally seeking out unregulated BZRAs over time and have developed dependence; however, the guidance in this document is grounded in evidence pertaining to prescribed BZRAs, which may limit direct applicability.
- Please see Clinical Bulletin: Benzodiazepine-adulterated Opioids for information relevant to individuals who have developed, or are at risk of developing, benzodiazepine withdrawal following the cessation of unregulated opioid use due to the adulteration of the unregulated opioid supply with benzodiazepines.

